Nurtec long term side effects - Common side effects of naratriptan may include: dizziness, drowsiness; feeling weak or tired; numbness or tingling; flushing (warmth, redness, or tingly feeling); nausea; or. pain or tightness in your jaw, neck, or throat. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

 
To date, long-term side effects haven’t been reported with Ajovy. Keep in mind that Ajovy is a recently approved medication in a new class of drugs. So, doctors are still learning about the drug .... Steven

Nurtec ODT may cause serious side effects including allergic reactions, including trouble breathing and rash. This can happen days after you take Nurtec ODT. Call your HCP or get emergency help right away if you have swelling of the face, mouth, tongue, or throat or trouble breathing. This occurred in less than 1% of patients treated with ... Nurtec ODT (rimegepant) is a brand-name prescription drug that's used to treat or help prevent migraine episodes. Learn about side effects, uses, and more.May 24, 2022 · Professional info. FAQ. Note: This document contains side effect information about ubrogepant. Some dosage forms listed on this page may not apply to the brand name Ubrelvy. Applies to ubrogepant: oral tablets. Side effects include: Nausea, somnolence (including sedation and fatigue ), dry mouth. Feb 1, 2023 · Kidney problems, severe (recent or long-term) or Liver disease or Patients who have recently received a GBCA or Seizures, history of—Use with caution. May cause side effects to become worse. Diabetes or Hypertension (high blood pressure)—Use with caution. May increase risk for more serious side effects. Mar 19, 2020 · NURTEC ODT is a drug used for treatment of acute migraine with or without aura in adults. A migraine is a type of headache that, in addition to pain, can be associated with nausea, vomiting, and ... Nurtec ODT (rimegepant) is a brand-name prescription drug that's used to treat or help prevent migraine episodes. Learn about side effects, uses, and more.FAQ Note: This document contains side effect information about rimegepant. Some dosage forms listed on this page may not apply to the brand name Nurtec ODT. Applies to rimegepant: oral orally disintegrating tablets. Side effects include: Acute treatment of migraine (≥1%): Nausea.Feb 24, 2023 · Other side effects include: asthenia, burning sensation, chest discomfort, neck pain, neck stiffness, numbness, throat irritation, feeling of heaviness, flushing, sensation of pressure, and sensation of tightness. Continue reading for a comprehensive list of adverse effects. Fioricet includes butalbital with acetaminophen and caffeine. Fiorinal is made with butalbital, aspirin, and caffeine. There are forms of each that also contain codeine . Codeine is an opiate drug, and it increases the risks of addiction and potential overdose. Butalbital relaxes the muscle tension believed to be associated with tension headaches.The most common side effects with the injection are bone, muscle and joint pains, flu like illness and headache. The flu like symptoms generally disappears after 24-48 hours and usually occurs only after the first injection. The most common side effects with the pill are diarrhea, pain in the extremities, and upset stomach.Jul 9, 2022 · How to take Overdose Ask your doctor Drug Images What is Nurtec ODT? If you have migraine, your doctor may suggest treatment with Nurtec ODT. It’s a prescription drug that’s used in adults to:... Jul 2, 2020 · Studies show that its migraine blocking effect can last up to 2 days. Nurtec is the only migraine stopping medication that has this long, beneficial effect to stop a migraine attack. Patients want a highly effective, quick acting migraine stopping medication wtih minimal side effects. Nurtec accomplishes all these. Nurtec ODT may cause serious side effects including allergic reactions, including trouble breathing and rash. This can happen days after you take Nurtec ODT. Call your HCP or get emergency help right away if you have swelling of the face, mouth, tongue, or throat or trouble breathing. This occurred in less than 1% of patients treated with ...Sep 29, 2022 · Rizatriptan may cause serious side effects. Stop using rizatriptan and call your doctor at once if you have: sudden and severe stomach pain and bloody diarrhea; cold feeling or numbness in your feet and hands; severe headache, blurred vision, pounding in your neck or ears; heart attack symptoms--chest pain or pressure, pain spreading to your ... Examples of mild side effects that have been reported with Ubrelvy include: sleepiness *. nausea *. fatigue (lack of energy) dry mouth *. * For more about this side effect, see the “Side effects ...May 31, 2023 · Nurtec ODT Has Minimal Side Effects. As with any medication, Nurtec OTC can have side effects. Studies showed that the side effects are minimal. The most common side effect experienced in 2% of patients was nausea. Other side effects included hypersensitivity reactions like shortness of breath and rash (less than 1%). Nurtec is not proved to be ... If you stop Nurtec and it goes away, for sure report to the company and/or FDA as a side effect/adverse event. Fortunately you don't have to taper off Nurtec- I'm in the process of trying to figure out if I'm having a side effect so I just stopped taking it last week. Edit: apparently there is some question as to cardiac effects of blocking CGRPSep 17, 2022 · Talk to your doctor if you want to stop taking Nurtec, particularly if they prescribed the medicine for long-term use. Don’t stop taking Nurtec without your doctor’s guidance. Nurtec and pregnancy. No conclusive studies have shown adverse effects of taking Nurtec during pregnancy for either the mother or baby. May 17, 2023 · The most common side effect of NURTEC ODT in acute treatment of migraine attacks with or without aura is: • nausea. The most common side effects of NURTEC ODT in preventive treatment of episodic migraine are: • nausea • stomach pain • indigestion. These are not the only possible side effects of NURTEC ODT. Call your doctor for medical ... Aug 30, 2023 · Fioricet includes butalbital with acetaminophen and caffeine. Fiorinal is made with butalbital, aspirin, and caffeine. There are forms of each that also contain codeine . Codeine is an opiate drug, and it increases the risks of addiction and potential overdose. Butalbital relaxes the muscle tension believed to be associated with tension headaches. Dizziness or lightheadedness. feeling of constant movement of self or surroundings. lack or loss of strength. loss of hair, temporary. sensation of spinning. uncontrolled eye movements. Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.See full list on healthline.com Qulipta can cause mild side effects. Examples that have been reported include: fatigue (low energy) decreased appetite. weight loss. nausea *. constipation *. increased liver enzymes, which may ...Nurtec has been the best abortive I've had next to Ubrelvy. Plus I finally got the prior Auth from tricare so no more samples yay. My only complaints about Nurtec is the taste, seriously why are all ODTs mint flavor, and it being so fragile. Seriously don't push it through the package, and make sure your hands are completely dry.Nov 20, 2022 · Nurtec ODT (rimegepant) is a brand-name prescription drug that's used to treat or help prevent migraine episodes. Learn about side effects, uses, and more. Mar 19, 2020 · NURTEC ODT is a drug used for treatment of acute migraine with or without aura in adults. A migraine is a type of headache that, in addition to pain, can be associated with nausea, vomiting, and ... Oct 5, 2022 · The first patient was treated with steroids with good relief, and the other patient refused treatment with steroids due to a history of side effects to steroids . Interestingly, when investigating headache as a predictor of COVID-19 clinical evolution, Caronna et al. demonstrated that headache predicted a shorter COVID-19 clinical course. Long-term effects Aimovig is a recently approved medication in a new class of drugs. As a result, there is very little long-term research available on Aimovig’s safety, and little is known about ...Uses. Zolpidem is used for a short time to treat a certain sleep problem ( insomnia) in adults. If you have trouble falling asleep, it helps you fall asleep faster, so you can get a better night's ...Fioricet includes butalbital with acetaminophen and caffeine. Fiorinal is made with butalbital, aspirin, and caffeine. There are forms of each that also contain codeine . Codeine is an opiate drug, and it increases the risks of addiction and potential overdose. Butalbital relaxes the muscle tension believed to be associated with tension headaches.feeling short of breath. fatigue (lack of energy) nausea. pain in the bones and muscles. hair loss *. Certain mild side effects that have been more commonly reported in children taking Sprycel ...Etanercept controls your body's defensive response by blocking the action of a certain natural substance (TNF) that is used by the immune system. Treatment decreases redness, itching and scaly ... Rizatriptan is used to treat acute migraine headaches with or without aura. It is not used to prevent migraine headaches and is not used for cluster headaches. Rizatriptan works in the brain to relieve the pain from migraine headaches. It belongs to the group of medicines called triptans. Many people find that their headaches go away completely ...Many people using this medication do not have serious side effects. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a ... The most common side effects of AJOVY include: injection site reactions; Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of AJOVY. For more information, ask your healthcare provider or pharmacist. Call your doctor for medical advice about side effects.May 23, 2021 · feeling short of breath. fatigue (lack of energy) nausea. pain in the bones and muscles. hair loss *. Certain mild side effects that have been more commonly reported in children taking Sprycel ... Rimegepant is used to treat acute migraine headaches with or without aura and prevent episodic migraine headaches. Rimegepant is not an ordinary pain reliever. It will not relieve pain other than from migraine headaches. This medicine is usually used for people whose headaches are not relieved by acetaminophen, aspirin, or other pain relievers.Oct 5, 2022 · The first patient was treated with steroids with good relief, and the other patient refused treatment with steroids due to a history of side effects to steroids . Interestingly, when investigating headache as a predictor of COVID-19 clinical evolution, Caronna et al. demonstrated that headache predicted a shorter COVID-19 clinical course. Mar 25, 2022 · For Healthcare Professionals General. The most commonly reported adverse reaction with acute use has been nausea; with preventive use, nausea,... Hypersensitivity. Hypersensitivity reactions including dyspnea and severe rash occurred in less than 1% of patients. Gastrointestinal. When do you take ... Incidence not known. Cracks in the skin. loss of heat from the body. painful or prolonged erections of the penis. scaly skin. swelling of the breasts or breast soreness in both females and males. unusual milk production. Other side effects not listed may also occur in some patients.This occurred in less than 1% of patients treated with Nurtec ODT. The most common side effects of Nurtec ODT were nausea (2.7%) and stomach pain/indigestion (2.4%). These are not the only possible side effects of Nurtec ODT. Tell your HCP if you have any side effects. CGRP inhibitors are a new class of drugs to prevent and treat chronic migraine and episodic migraine. The FDA-approved migraine medication works well and has few side effects. Studies show that its migraine blocking effect can last up to 2 days. Nurtec is the only migraine stopping medication that has this long, beneficial effect to stop a migraine attack. Patients want a highly effective, quick acting migraine stopping medication wtih minimal side effects. Nurtec accomplishes all these.Feb 24, 2023 · itching, pain, redness, or swelling. lightheadedness, dizziness, or fainting. nerve pain. severe numbness, especially on one side of the face or body. severe or continuing stomach pain. trouble speaking or swallowing. twitching. unusual bleeding or bruising. vomiting of blood or material that looks like coffee grounds. Generic Name (S): butalbital-acetaminophen-caff. Warnings: One ingredient in this product is acetaminophen. Taking too much acetaminophen may cause serious (possibly fatal) liver disease. Adults ...dizziness. tingling. tiredness or drowsiness. feeling cold or warm. pain, pressure, or tightness in the jaw, neck, or throat*. * To learn more about this side effect, see the “Side effects ...Jul 9, 2022 · How to take Overdose Ask your doctor Drug Images What is Nurtec ODT? If you have migraine, your doctor may suggest treatment with Nurtec ODT. It’s a prescription drug that’s used in adults to:... Generic Name (S): aspirin-acetaminophen-caffeine. Warnings: One ingredient in this product is acetaminophen. Taking too much acetaminophen may cause serious (possibly fatal) liver disease. Adults ... Sep 29, 2022 · Rizatriptan may cause serious side effects. Stop using rizatriptan and call your doctor at once if you have: sudden and severe stomach pain and bloody diarrhea; cold feeling or numbness in your feet and hands; severe headache, blurred vision, pounding in your neck or ears; heart attack symptoms--chest pain or pressure, pain spreading to your ... Dec 14, 2020 · 27% Concerned about side effects. 21% Concerned about long-term safety. 19% Can’t afford them. 14% Insurance won’t cover. CGRP medications are not cheap. Eight doses of Nurtec, the acute CGRP endorsed by Kardashian, can cost over $1,000 without insurance. itching, pain, redness, or swelling. lightheadedness, dizziness, or fainting. nerve pain. severe numbness, especially on one side of the face or body. severe or continuing stomach pain. trouble speaking or swallowing. twitching. unusual bleeding or bruising. vomiting of blood or material that looks like coffee grounds.Naproxen is used to relieve pain from various conditions such as headache, muscle aches, tendonitis, dental pain, and menstrual cramps. It also reduces pain, swelling, and joint stiffness caused ...The other symptoms of migraine--especially fatigue, nausea and confusion--are alive and well though, lol. Nurtec is my miracle drug. No side effect, just amazing relief. I had terrible side effects to triptans and even Ubrevtly, so im honestly in love with nurtec.In comparison, liraglutide 3.0 mg, at a clinical dose of 3.0 mg, is also approved for weight management and has been associated with placebo-subtracted weight losses of 4.5–6.0 kg. 4, 27 While there are beneficial effects such as improved HbA1c levels, there are some more severe rare side effects such as gallstones and pancreatitis. 194 In ...Nurtec ODT (rimegepant) can cause serious allergic reactions. This might happen as early as a few days after you start treatment. Symptoms can include a rash, swelling of the face and eyes, swollen throat, or trouble breathing. If you experience these symptoms, stop Nurtec ODT (rimegepant) and get medical help right away.Rizatriptan may cause serious side effects. Stop using rizatriptan and call your doctor at once if you have: sudden and severe stomach pain and bloody diarrhea; cold feeling or numbness in your feet and hands; severe headache, blurred vision, pounding in your neck or ears; heart attack symptoms--chest pain or pressure, pain spreading to your ...Jun 28, 2018 · In several years, we will have more information, regarding long-term safety and physiological effects of the CGRP antagonists. Short-term, these have been well tolerated. Until we know more, clinicians will have to decide which patients should not be given a CGRP antagonist using a combination of available evidence, clinical judgment, patient ... The following clinically significant adverse reactions are discussed in greater detail in other sections of the labeling: Hypersensitivity Reactions [see Warnings and Precautions (5.1) ] Acute treatment of migraine: the adverse reaction reported in ≥ 1% of patients treated with NURTEC ODT is nausea. ( 6.1 ) Preventive treatment of episodic migra...Mostly due to the side effects. Diarrhea, nausea, stomach pain, horrible indigestion, head pain/ brain zaps, dizzy, achey. I couldn't sleep one bit, and I am scared to try it again. I'm scared to try any migraine prescriptions again. I am one who seems to always get the unbearable side effects.The first patient was treated with steroids with good relief, and the other patient refused treatment with steroids due to a history of side effects to steroids . Interestingly, when investigating headache as a predictor of COVID-19 clinical evolution, Caronna et al. demonstrated that headache predicted a shorter COVID-19 clinical course.May 23, 2021 · feeling short of breath. fatigue (lack of energy) nausea. pain in the bones and muscles. hair loss *. Certain mild side effects that have been more commonly reported in children taking Sprycel ... Rimegepant is used to treat acute migraine headaches with or without aura and prevent episodic migraine headaches. Rimegepant is not an ordinary pain reliever. It will not relieve pain other than from migraine headaches. This medicine is usually used for people whose headaches are not relieved by acetaminophen, aspirin, or other pain relievers.Nov 20, 2022 · Nurtec ODT (rimegepant) is a brand-name prescription drug that's used to treat or help prevent migraine episodes. Learn about side effects, uses, and more. Generic Name (S): butalbital-acetaminophen-caff. Warnings: One ingredient in this product is acetaminophen. Taking too much acetaminophen may cause serious (possibly fatal) liver disease. Adults ... The other symptoms of migraine--especially fatigue, nausea and confusion--are alive and well though, lol. Nurtec is my miracle drug. No side effect, just amazing relief. I had terrible side effects to triptans and even Ubrevtly, so im honestly in love with nurtec.Sep 17, 2022 · Talk to your doctor if you want to stop taking Nurtec, particularly if they prescribed the medicine for long-term use. Don’t stop taking Nurtec without your doctor’s guidance. Nurtec and pregnancy. No conclusive studies have shown adverse effects of taking Nurtec during pregnancy for either the mother or baby. More common side effects. The common side effect that can occur with both Emgality and Ajovy (when taken individually) is an injection site reaction. This reaction can cause symptoms such as ...Studies show that its migraine blocking effect can last up to 2 days. Nurtec is the only migraine stopping medication that has this long, beneficial effect to stop a migraine attack. Patients want a highly effective, quick acting migraine stopping medication wtih minimal side effects. Nurtec accomplishes all these.Nurtec ODT may cause serious side effects including allergic reactions, including trouble breathing and rash. This can happen days after you take Nurtec ODT. Call your HCP or get emergency help right away if you have swelling of the face, mouth, tongue, or throat or trouble breathing. This occurred in less than 1% of patients treated with ...Completely kills the headache for me without side effects (like the strong, almost painful tingling sensation from heat after rizatriptan). Going to look at using Nurtec's "OneSource" program to see if I can get my insurance to cover more of it, because I'm sure the patent has at least 15 years left on it so there won't be a generic rimegepant ...Jan 3, 2022 · Marijuana is a drug and it is harmful to individual’s long-term health. Weed has many side effects and the consequences are different to each person who uses it, especially when mixed with nurtec. If you take nurtec, and also drink Alcohol or MDMA, you can research the effects of nurtec and Alcohol, nurtec and Cocaine as well as nurtec and ... Long-term side effects can be prevented by instilling control over the length of treatment. In rare cases of severe intolerance, an individual will have to switch to a different drug. For instance, in Imodium vs Pepto-Bismol comparison, Pepto-Bismol wins by having more applications, and it can be used to help with nausea and heartburn as well ...feeling short of breath. fatigue (lack of energy) nausea. pain in the bones and muscles. hair loss *. Certain mild side effects that have been more commonly reported in children taking Sprycel ...Completely kills the headache for me without side effects (like the strong, almost painful tingling sensation from heat after rizatriptan). Going to look at using Nurtec's "OneSource" program to see if I can get my insurance to cover more of it, because I'm sure the patent has at least 15 years left on it so there won't be a generic rimegepant ... Mar 5, 2023 · These drugs tend to cause different side effects, but can cause some similar ones. With Qulipta, nausea, constipation, and fatigue (low energy) were most common in studies. In Topamax’s studies ... Common verapamil side effects may include: nausea, constipation; infections, flu symptoms; swelling in lower legs or hands; headache, dizziness; or. low blood pressure. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.Examples of Nurtec ODT’s more commonly reported side effects include: nausea * belly pain indigestion * * To learn more about this side effect, see the “Side effects explained” section...Jul 2, 2020 · Studies show that its migraine blocking effect can last up to 2 days. Nurtec is the only migraine stopping medication that has this long, beneficial effect to stop a migraine attack. Patients want a highly effective, quick acting migraine stopping medication wtih minimal side effects. Nurtec accomplishes all these. Long-term effects Aimovig is a recently approved medication in a new class of drugs. As a result, there is very little long-term research available on Aimovig’s safety, and little is known about ...Common side effects of naratriptan may include: dizziness, drowsiness; feeling weak or tired; numbness or tingling; flushing (warmth, redness, or tingly feeling); nausea; or. pain or tightness in your jaw, neck, or throat. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.Common side effects of naratriptan may include: dizziness, drowsiness; feeling weak or tired; numbness or tingling; flushing (warmth, redness, or tingly feeling); nausea; or. pain or tightness in your jaw, neck, or throat. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.The difference between Emgality and Nurtec is that while Emgality is a preventive treatment, Nurtec is an acute treatment for a person with a migraine problem. They also differ when it comes to their side effects and the things they interact with. Also, they have different doses and chemical names. Emgality is a type of injection used as a ...

To date, long-term side effects haven’t been reported with Ajovy. Keep in mind that Ajovy is a recently approved medication in a new class of drugs. So, doctors are still learning about the drug .... Spark submit files

nurtec long term side effects

Jul 2, 2020 · Studies show that its migraine blocking effect can last up to 2 days. Nurtec is the only migraine stopping medication that has this long, beneficial effect to stop a migraine attack. Patients want a highly effective, quick acting migraine stopping medication wtih minimal side effects. Nurtec accomplishes all these. Some people feel dizzy or drowsy during or after a migraine, or after taking rizatriptan to relieve a migraine. As long as you are feeling dizzy or drowsy, do not drive, use machines, or do anything else that could be dangerous if you are dizzy or not alert. This medicine may increase your blood pressure.Aug 1, 2023 · Some people feel dizzy or drowsy during or after a migraine, or after taking rizatriptan to relieve a migraine. As long as you are feeling dizzy or drowsy, do not drive, use machines, or do anything else that could be dangerous if you are dizzy or not alert. This medicine may increase your blood pressure. Nurtec ODT (rimegepant) is a brand-name prescription drug that's used to treat or help prevent migraine episodes. Learn about side effects, uses, and more.Feb 22, 2023 · Examples of mild side effects that have been reported with Ubrelvy include: sleepiness *. nausea *. fatigue (lack of energy) dry mouth *. * For more about this side effect, see the “Side effects ... Other side effects include: asthenia, burning sensation, chest discomfort, neck pain, neck stiffness, numbness, throat irritation, feeling of heaviness, flushing, sensation of pressure, and sensation of tightness. Continue reading for a comprehensive list of adverse effects.Medication overuse headaches — also known as rebound headaches — are caused by the long-term use of medicines to treat headaches such as migraines. Pain relievers offer relief for occasional headaches. But if you take them more than a couple of days a week, they may trigger headaches. If you have a headache disorder such as migraine, most ...In Nurtec ODT’s clinical studies, these were some of the side effects that occurred more often: indigestion * abdominal pain* nausea* * For more information about this side effect, see “ Nurtec ODT: Side effects explained ” below. Nurtec ODT: Mild side effects Nurtec ODT can cause mild side effects, which are listed below.Feb 27, 2023 · Lorazepam may increase the risk of depression or unmask depression or increase the risk of suicidal thoughts. Monitor for worsening of mood. Lorazepam is potentially addictive and may cause both emotional and physical dependence. The lowest dose should be used for the shortest possible time. Nurtec ODT Has Minimal Side Effects. As with any medication, Nurtec OTC can have side effects. Studies showed that the side effects are minimal. The most common side effect experienced in 2% of patients was nausea. Other side effects included hypersensitivity reactions like shortness of breath and rash (less than 1%). Nurtec is not proved to be ...Some people feel dizzy or drowsy during or after a migraine, or after taking rizatriptan to relieve a migraine. As long as you are feeling dizzy or drowsy, do not drive, use machines, or do anything else that could be dangerous if you are dizzy or not alert. This medicine may increase your blood pressure.Generic Name (S): butalbital-acetaminophen-caff. Warnings: One ingredient in this product is acetaminophen. Taking too much acetaminophen may cause serious (possibly fatal) liver disease. Adults ...Jun 16, 2022 · Long-term effects Aimovig is a recently approved medication in a new class of drugs. As a result, there is very little long-term research available on Aimovig’s safety, and little is known about ... Nurtec ODT Has Minimal Side Effects. As with any medication, Nurtec OTC can have side effects. Studies showed that the side effects are minimal. The most common side effect experienced in 2% of patients was nausea. Other side effects included hypersensitivity reactions like shortness of breath and rash (less than 1%). Nurtec is not proved to be ...Naproxen is used to relieve pain from various conditions such as headache, muscle aches, tendonitis, dental pain, and menstrual cramps. It also reduces pain, swelling, and joint stiffness caused ...The most common side effect of NURTEC ODT in acute treatment of migraine attacks with or without aura is: • nausea. The most common side effects of NURTEC ODT in preventive treatment of episodic migraine are: • nausea • stomach pain • indigestion. These are not the only possible side effects of NURTEC ODT. Call your doctor for medical ...Our Nurtec ODT (rimegepant) Orally Disintegrating Tablets, for Sublingual or Oral Use Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side ...Uses. Fluticasone is used to relieve seasonal and year-round allergic and non-allergic nasal symptoms, such as stuffy/ runny nose, itching, and sneezing. It can also help relieve allergy eye ...Follow-Up Study Data on Efficacy for Chronic Migraine. In the follow-up study, efficacy was analyzed using three Qulipta treatment groups: 30 mg twice daily, 60 mg once daily, and placebo. Both nonplacebo groups showed similar results after 12 weeks, with participants reporting statistically significant reductions from baseline in mean monthly ....

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